Infectious diseases
Sexually transmitted diseases
Chlamydia trachomatis
Chlamydia trachomatis is an intracellular bacterium responsible for one of the most prevalent sexually transmitted infections, linked to urethritis, cervicitis, neonatal conjunctivitis, and trachoma.
Available controls:
Treponema pallidum (Syphilis)
Treponema pallidum is a spirochete bacterium that causes syphilis, a sexually transmitted disease with multiple stages that may result in systemic damage if untreated.
Available controls:
Human Papillomavirus (HPV)
HPV is a DNA virus that infects epithelial tissues, causing common and genital warts as well as cervical precancerous lesions linked to high-risk genotypes.
Available controls:
Trichomonas vaginalis
Trichomonas vaginalis is a sexually transmitted protozoan parasite that commonly affects women, leading to abnormal discharge, irritation, and genital discomfort.
Available controls:
Neisseria gonorrhoeae
Neisseria gonorrhoeae is a Gram-negative bacterium responsible for gonorrhea, a common STI that can lead to pelvic inflammatory disease and infertility if untreated.
Available controls:
Gardnerella vaginalis
Gardnerella vaginalis is associated with bacterial vaginosis, a condition resulting from an imbalance in the vaginal microbiota, linked to increased risk of STIs and obstetric complications.
Available controls:
Atopobium vaginae
Atopobium vaginae is frequently found in women with bacterial vaginosis (BV), a common vaginal infection. It can cause symptoms like discharge, irritation, or odor, though many cases are asymptomatic. Diagnosis is more reliable using molecular techniques like multiplex PCR.
Ureaplasma parvum
Ureaplasma parvum is a bacterium of the genus Ureaplasma and family Mycoplasmataceae, which is part of the normal genital microbiota, but can behave as a pathogen. It is associated with urethritis, vaginitis, pelvic inflammatory disease, infertility and pregnancy complications. It can also affect the newborn, causing sepsis or meningitis. It is detected by PCR or specialised culture.
Available controls:
AMPLIRUN® UREAPLASMA PARVUM DNA CONTROL (Ref. MBC133-R)
Ureaplasma urealyticum
Ureaplasma urealyticum is a bacterium of the genus Ureaplasma and of the family Mycoplasmataceae, characterised by the absence of a cell wall. It colonises the urogenital tract of a large percentage of healthy adults, especially women, where it can behave as a commensal. However, under certain circumstances, it can act as an opportunistic pathogen associated with urethritis, vaginitis, chorioamnionitis, premature delivery and neonatal complications. Infection is sexually transmitted and diagnosis is by specialised culture or molecular techniques such as PCR.
Available controls:
AMPLIRUN® UREAPLASMA UREALYTICUM DNA CONTROL (MBC112)
Mycoplasma hominis
Mycoplasma hominis is a cell wall–lacking bacterium belonging to the family Mycoplasmataceae that colonizes the human genitourinary tract. It is primarily transmitted through sexual contact and can cause urinary infections, vaginitis, and pregnancy complications. Although many infections are asymptomatic, it can cause fever, pelvic pain, and vaginal discharge. Diagnosis is performed through specific culture or PCR.
Available controls:
AMPLIRUN® MYCOPLASMA HOMINIS DNA CONTROL (Ref. MBC084)
Mycoplasma genitalium
Mycoplasma genitalium is a cell wall–lacking bacterium that colonizes the human urogenital tract and is primarily transmitted through sexual contact. It is associated with nongonococcal urethritis, cervicitis, and pelvic inflammatory disease. Many infections can be asymptomatic but may also cause pain during urination, discharge, and pelvic discomfort. Diagnosis is performed by PCR due to the difficulty of culturing the organism.
Available controls:
AMPLIRUN® MYCOPLASMA GENITALIUM DNA CONTROL (Ref. MBC085)
AMPLIRUN® TOTAL MACROLIDE RESISTANT MGE CONTROL PANEL (SWAB) (Ref. MBTC029)
Haemophilus ducreyi
Haemophilus ducreyi is a gram-negative bacterium that causes chancroid, a sexually transmitted infection that is uncommon in developed countries. It presents with painful genital ulcers and inguinal lymphadenopathy. It mainly affects sexually active individuals in tropical and subtropical regions. Diagnosis is based on clinical presentation, culture, or PCR.
Available controls:
AMPLIRUN® HAEMOPHILUS DUCREYI DNA CONTROL (Ref. MBC021-R)
Herpes simplex virus
Herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) are DNA viruses from the Herpesviridae family that cause recurrent mucocutaneous infections. HSV-1 is commonly associated with oral herpes, while HSV-2 is more frequently linked to genital herpes. Infection may be asymptomatic or present with painful vesicular lesions. Diagnosis is made by PCR or serology.
Available controls:
AMPLIRUN® HERPES SIMPLEX 1 DNA CONTROL (Ref. MBC023)
AMPLIRUN® HERPES SIMPLEX 2 DNA CONTROL (Ref. MBC024)
Gardnerella vaginalis
Gardnerella vaginalis is a gram-variable bacterium that is part of the normal vaginal microbiota in small amounts. Its overgrowth is associated with bacterial vaginosis (BV), a common vaginal infection in women of childbearing age.
Available controls:
AMPLIRUN® GARDNERELLA VAGINALIS DNA CONTROL (Ref. MBC108-R)
Macrolide resistant MGE
Macrolide resistant MGE refers to mobile genetic elements that carry genes for resistance to macrolides, an important class of antibiotics. It is not a specific organism, but a mechanism of dissemination of antimicrobial resistance. They usually carry bacteria such as Streptococcus pneumoniae, Staphylococcus aureus, Enterococcus spp, Mycoplasma genitalium or Campylobacter spp.
Available controls:
AMPLIRUN® TOTAL MACROLIDE RESISTANT MGE CONTROL PANEL (SWAB) (Ref. MBTC029)
Vector-borne diseases
Chagas Disease
Chagas disease is caused by Trypanosoma cruzi, a parasite mainly transmitted by triatomine insects in Latin America. It can also spread via blood transfusion, congenital transmission, or lab exposure.
Available controls:
Dengue
Dengue virus is mosquito-borne (Aedes spp.) and among the fastest-spreading viral diseases worldwide, with millions of cases yearly in tropical and subtropical regions.
Available controls:
Zika Virus
Zika virus is a flavivirus transmitted by Aedes mosquitoes that may cause mild symptoms, but can also lead to neurological issues and congenital microcephaly in newborns.
Available controls:
West Nile Virus
West Nile virus is an emerging mosquito-borne flavivirus that may cause mild illness or serious neuroinvasive disease in humans. It has a wide global distribution.
Available controls:
Toscana Virus (TOSV)
Toscana virus is a Phlebovirus transmitted by sandflies, associated with seasonal viral meningitis in Mediterranean countries of southern Europe.
Available controls:
Chikungunya virus
Chikungunya virus is an RNA virus of the genus Alphavirus, transmitted by Aedes aegypti and Aedes albopictus mosquitoes. It causes sudden fever, severe joint pain, rash, nausea and fatigue. It is generally not fatal, but can cause complications in infants and vulnerable people. Diagnosis is made by molecular or serological tests. There is no vaccine or specific treatment; rest, analgesics and good hydration are indicated.
Available controls:
AMPLIRUN® CHIKUNGUNYA VIRUS RNA CONTROL (Ref. MBC099-R)
AMPLIRUN® TOTAL ZIKV/DENV/CHIKV CONTROL (PLASMA) (Ref. MBTC023)
Japanese encephalitis
Japanese encephalitis virus belongs to the genus Flavivirus and is transmitted by mosquitoes of the genus Culex. The main reservoirs are pigs and waterfowl. Most infections are asymptomatic, but in some cases it can cause encephalitis with fever, headache, convulsions and neurological disturbances. There is no specific treatment; prevention is based on vaccination and vector control.
Available controls:
AMPLIRUN® JAPANESE ENCEPHALITIS RNA CONTROL (Ref. MBC134-R).
Plasmodium spp.
Plasmodium is a genus of apicomplexan protists responsible for malaria. It is transmitted by the bite of mosquitoes of the genus Anopheles. In humans, the most relevant species are P. falciparum, P. vivax, P. ovale and P. malariae. The life cycle includes hepatic and erythrocytic phases, and infection can range from mild febrile to severe forms with anaemia, coma or death. Diagnosis is made by microscopy or rapid antigen tests.
Available controls:
AMPLIRUN® PLASMODIUM FALCIPARUM DNA CONTROL (Ref. MBC148-R)
Mayaro virus
Mayaro disease is a viral infection belonging to the genus Alphavirus, transmitted by mosquitoes. It causes fever, rash, headache and joint pain. It is found mainly in jungle and rural areas of South America and is considered endemic in tropical forests.
Available controls:
AMPLIRUN® MAYARO VIRUS RNA CONTROL (Rf. MBC153-R)
Oropuche virus
Oropouche syndrome is a viral disease endemic in some areas of Latin America and the Caribbean. It is transmitted by insects and presents flu-like symptoms such as fever, headache, muscle and joint pain, including nausea and vomiting.
Available controls:
AMPLIRUN® OROPOUCHE VIRUS RNA CONTROL (Ref. MBC152-R)
Ross River Virus
Ross River virus, transmitted by different species of mosquitoes, is endemic in Australia, Papua New Guinea and Solomon Islands, the main reservoirs being kangaroos and wallabies. It usually causes arthralgias, fever, headache, skin lesions and fatigue.
Available controls:
AMPLIRUN® ROSS RIVER VIRUS RNA CONTROL (Ref. MBC130-R)
Tick-borne encephalitis
Tick-borne encephalitis is a viral disease caused by a virus, an arbovirus of the genus Flavivirus, which affects the central nervous system. It is endemic in certain areas of Central and Eastern Europe and parts of Asia.
Available controls:
AMPLIRUN® TICK-BORNE ENCEPHALITIS VIRUS RNA CONTROL (Ref. MBC045-R)
Leishmania infantum
Leishmania infantum is a protozoan parasite of the genus Leishmania that is transmitted to humans and animals (essentially dogs) through mosquito bites. It can cause the most deadly variant of leishmaniasis in humans.
Available controls:
AMPLIRUN® LEISHMANIA INFANTUM DNA CONTROL (Ref. MBC032-R)
Leishmania chagasi
Leishmania chagasi also known as leishmania infantum is a zoonosis, with dogs being the main reservoir. It can cause prolonged fever, weight loss, enlargement of the spleen or liver and anemia in humans.
Available controls:
AMPLIRUN® LEISHMANIA CHAGASI DNA CONTROL (Ref. MBC060-R)
Venezuelan Equine Encephalitis
Venezuelan Equine Encephalitis is a zoonotic viral disease caused by Venezuelan equine encephalitis virus, an alphavirus of the Togaviridae family. It usually presents a mild picture in humans but progresses to encephalitis.
Available controls:
AMPLIRUN® VENEZUELAN EQUINE ENCEPHALITIS VIRUS RNA CONTROL (Ref. MBC096-R)
Eastern equine encephalitis
Eastern Equine Encephalitis is a severe viral disease caused by a mosquito-borne alphavirus that affects equines and humans. Although rare in humans, it can cause severe encephalitis with a high mortality rate.
Available controls:
AMPLIRUN® EASTERN EQUINE ENCEPHALITIS RNA CONTROL (Ref. MBC097-R)
Yellow fever
Yellow fever is an acute viral and hemorrhagic disease caused by a mosquito-borne flavivirus. It causes muscle pain, vomiting, headache and fever in its acute phase, and may progress to jaundice, hemorrhages and liver and kidney damage in its toxic phase, with high mortality.
Available controls:
AMPLIRUN® YELLOW FEVER VIRUS RNA CONTROL (Ref. MBC100-R)
St. Louis encephalitis
St. Louis encephalitis is a viral disease of the central nervous system caused by a mosquito-borne flavivirus. It causes viral encephalitis that can lead to coma and/or permanent damage and even death in severe cases.
Available controls:
AMPLIRUN® ST LOUIS ENCEPHALITIS VIRUS RNA CONTROL (Ref. MBC101-R)
Orientia tsutsugamushi
Orientia tsutsugamushi is an obligate intracellular bacterium that causes the disease called Tsutsugamushi or scrub typhus fever. It is transmitted by the bite of infected trombiculine mite larvae and causes sudden high fever, severe headache, joint muscle pain and rash among others.
Available controls:
AMPLIRUN® ORIENTIA TSUTSUGAMUSHI DNA CONTROL (Ref. MBC106-R)
Rickettsia
Rickettsia conorii is an obligate intracellular Gram-negative bacterium of the Rickettsiaceae family. It is the causative agent of Mediterranean spotted fever, a tick-borne infectious disease endemic to Mediterranean countries, with seasonal peaks during spring and summer. The disease is transmitted to humans through the bite of infected ticks, mainly of the Rhipicephalus genus.
Vaccine-preventable diseases
Measles
Measles is a highly contagious viral illness primarily affecting children. Despite widespread vaccination, outbreaks continue to appear, especially in under-immunized populations. Severe complications include encephalitis and subacute sclerosing panencephalitis.
Available controls:
Mumps
The mumps virus causes swelling of the parotid salivary glands and is a leading cause of aseptic meningitis. It can also result in complications like orchitis, pancreatitis, or ovarian inflammation.
Available controls:
Varicella-Zoster Virus
Varicella-Zoster Virus (VZV) is a herpesvirus responsible for chickenpox and shingles. After primary infection, the virus remains dormant in the body and may reactivate later in life.
Available controls:
Rubella
Rubella is an exanthematous viral disease, contagious but generally mild, whose main medical importance lies in its teratogenic effect when affecting pregnant women, which can cause congenital cataracts, deafness and congenital heart disease.
Available controls:
AMPLIRUN® RUBELLA RNA CONTROL (Ref. MBC113-R)
Fungal infections
Candida albicans
Candida albicans is an opportunistic yeast that can cause anything from superficial infections to severe invasive candidiasis, especially in immunocompromised patients. It commonly colonizes the skin, vagina, and gastrointestinal tract.
Available controls:
Aspergillus fumigatus
Aspergillus fumigatus is an airborne fungus capable of triggering respiratory conditions ranging from allergic reactions to invasive aspergillosis in immunocompromised hosts. It is widespread in the environment.
Available controls:
Pneumocystis jirovecii
Pneumocystis jirovecii is an opportunistic fungus that causes severe pneumonia (PcP) in immunocompromised patients. It cannot be cultured and is diagnosed using molecular or immunofluorescence-based techniques.
Candida auris
Candida auris is a fungus that can cause a serious infection in the bloodstream and organs. It usually affects people who already have another disease, so its diagnosis is complicated by the fact that it is difficult to distinguish its symptoms from those of other infections.
Available controls:
AMPLIRUN® CANDIDA AURIS DNA CONTROL (Ref. MBC127-R)
Cryptococcus neoformans
Cryptococcus neoformans is an encapsulated fungus found in plants and animals. It can cause cryptococcosis, an infection that mainly affects people with weakened immune systems. Its most serious form is cryptococcal meningitis, an infection of the brain that can affect the lungs and other organs.
Available controls:
AMPLIRUN® CRYPTOCOCCUS NEOFORMANS DNA CONTROL (Ref. MBC015-R)
Aspergillus flavus
Aspergillus flavus is an opportunistic fungus of the genus Aspergillus, widely distributed in nature that can contaminate food with substances and cause diseases such as invasive aspergillosis or fungal otitis externa among others.
Aspergillus niger
Aspergillus niger is a fungus of the genus Aspergillus common in the environment. It can cause otomycosis, pulmonary aspergillosis (rarely invasive) and chronic fungal sinusitis.
Aspergillus terreus
Aspergillus terreus is a filamentous fungus of the genus Aspergillus found in soil, dust and decaying plant matter. It can cause invasive pulmonary aspergillosis and spread to other organs, especially in immunocompromised individuals.
Gastrointestinal infections
Helicobacter pylori
Helicobacter pylori is a stomach-infecting bacterium linked to gastritis, gastric and duodenal ulcers, and increased risk of gastric cancer. It is more common in developing countries.
Available controls:
Clostridioides difficile
Clostridioides difficile is a bacterium that causes intestinal infections, especially in hospital settings after antibiotic use. It’s the most common cause of healthcare-associated diarrhea, with severity ranging from mild cases to pseudomembranous colitis. Diagnosis involves antigen/toxin detection or molecular tests like PCR.
Available controls:
AMPLIRUN® CLOSTRIDIUM DIFFICILE DNA CONTROL (Ref. MBC043-R)
AMPLIRUN® TOTAL CLOSTRIDIUM DIFFICILE RT027 CONTROL (STOOL) (Ref. MBTC026-R)
AMPLIRUN® TOTAL GASTROINTESTINAL BACTERIAL PANEL CONTROL (STOOL) (Ref. MBTC021)
👉 Learn more about Clostridioides difficile at Vircell
Escherichia coli (E. coli)
E. coli is a Gram-negative bacterium common in the human gut. Although many strains are harmless, some are pathogenic and cause diarrhoea, urinary tract infections or septicaemia. The most important variants include: EPEC, ETEC, EHEC, EIEC and EAEC. Shiga toxin-producing strains (STEC/EHEC) can trigger severe conditions such as haemorrhagic colitis and haemolytic uraemic syndrome (HUS).
Available controls:
AMPLIRUN® ESCHERICHIA COLI (EAEC) DNA CONTROL (Ref. MBC121-R)
AMPLIRUN® ESCHERICHIA COLI (EIEC) DNA CONTROL (Ref. MBC122-R)
AMPLIRUN® ESCHERICHIA COLI (EPEC) DNA CONTROL (Ref. MBC123-R)
AMPLIRUN® ESCHERICHIA COLI (ETEC) DNA CONTROL (Ref. MBC124-R)
AMPLIRUN® TOTAL GASTROINTESTINAL BACTERIAL PANEL CONTROL (STOOL) (MBTC021)
AMPLIRUN® ESCHERICHIA COLI (VTEC) DNA CONTROL (Ref. MBC022-R)
Norovirus
Norovirus is a highly contagious RNA virus that causes outbreaks of acute gastroenteritis with vomiting, diarrhoea and abdominal pain. It is easily transmitted by contaminated food or water, person-to-person contact or infected surfaces. It is a leading cause of viral gastroenteritis worldwide, affecting people of all ages, especially in closed environments.
Available controls:
AMPLIRUN® NOROVIRUS RNA CONTROL (Ref. MBC111-R)
Rotavirus
Rotavirus is a double-stranded RNA virus that causes severe diarrhoea in children under 5 years of age and animal neonates. It is transmitted by the faecal-oral route and has a high morbidity in developing countries. Almost all children have had a rotavirus infection before the age of 5 years. In animals, such as calves, it can cause neonatal diarrhoea, leading to economic losses in animal husbandry.
Available controls:
AMPLIRUN® ROTAVIRUS RNA CONTROL (Ref. MBC026-R)
Adenovirus
Adenoviruses are non-enveloped DNA viruses that can infect both humans and animals. They cause respiratory infections, gastroenteritis, conjunctivitis and haemorrhagic cystitis. Their ability to remain in the environment and their high transmissibility make them relevant in outbreaks. In addition, they are used as vectors in gene therapies and vaccines because of their efficiency in gene transfer.
Available controls:
AMPLIRUN® ADENOVIRUS DNA CONTROL (Ref. MBC001)
AMPLIRUN® ADENOVIRUS 41 DNA CONTROL (Ref. MBC114-R)
Sapovirus
Sapovirus is an RNA virus of the genus Caliciviridae that causes acute gastroenteritis, mainly in children. Together with norovirus, it is a major cause of outbreaks of viral diarrhoea. It is transmitted by faecal-oral route, contaminated food or close contact. It causes watery diarrhoea, nausea and vomiting, with symptoms usually resolving within a few days.
Available controls:
AMPLIRUN® SAPOVIRUS RNA CONTROL (Ref. MBC151-R)
Salmonella
Salmonella is a genus of Gram-negative, flagellated, facultative anaerobic bacteria. It is found in animals and humans, and can cause salmonellosis, a gastrointestinal infection through consumption of contaminated food, especially meat or eggs. S. enterica is the most pathogenic species, and in some cases can invade the bloodstream and cause systemic illness.
Available controls:
AMPLIRUN® SALMONELLA ENTERITIDIS DNA CONTROL (Ref. MBC003-R)
AMPLIRUN® SALMONELLA TYPHI DNA CONTROL (Ref. MBC044-R)
Entamoeba histolytica
Entamoeba histolytica is a parasitic protozoan responsible for amoebiasis, an intestinal disease also known as amoebic dysentery. It is transmitted mainly by ingestion of food or water contaminated with cysts of the parasite, which can survive in the environment. In most cases, the infection is asymptomatic, but can cause symptoms such as diarrhoea, abdominal pain, colitis and, in more severe cases, dysentery or liver abscesses.
Giardia lamblia
Giardia lamblia, also known as G. intestinalis or G. duodenalis, is a flagellate protozoan that inhabits the small intestine of humans and other mammals. It is the causative agent of giardiasis, an intestinal disease characterised by watery diarrhoea, malabsorption and abdominal pain. It is transmitted mainly by the faecal-oral route, through contaminated food or water.
Available controls:
AMPLIRUN® GIARDIA INTESTINALIS DNA CONTROL (Ref. MBC119-R)
Cryptosporidium spp.
Cryptosporidium is a genus of apicomplexan protists that causes cryptosporidiosis, a faecal-oral diarrhoeal disease. Unlike other apicomplexans such as Plasmodium or Toxoplasma, Cryptosporidium does not require vectors and completes its life cycle in a single host. It is transmitted by ingestion of resistant oocysts present in contaminated food or water. In healthy people, it usually causes self-limiting diarrhoea, but in young or immunocompromised children it can cause prolonged or severe infections. The most common species in humans are C. hominis and C. parvum.
Available controls:
AMPLIRUN® CRYPTOSPORIDIUM PARVUM DNA CONTROL (Ref. MBC126-R)
Campylobacter spp.
Campylobacter is a genus of Gram-negative, spiral-shaped bacteria, considered a major cause of gastroenteritis worldwide. The most common species is Campylobacter jejuni, although C. coli, C. lari and others have also been implicated. Infection is mainly acquired through consumption of contaminated food. Symptoms include diarrhoea, fever, abdominal pain and, in rare cases, complications such as Guillain-Barré syndrome. Campylobacteriosis is especially common and severe in young children and immunocompromised persons.
Available controls:
AMPLIRUN® TOTAL GASTROINTESTINAL BACTERIAL PANEL CONTROL (STOOL) (Ref. MBTC021).
AMPLIRUN® CAMPYLOBACTER JEJUNI DNA CONTROL (Ref. MBC088-R)
Astrovirus
Astroviruses are non-enveloped single-stranded positive RNA viruses belonging to the family Astroviridae. They are a common cause of viral gastroenteritis, especially in children, the elderly and immunocompromised individuals. Infection produces mild to moderate symptoms such as diarrhoea, nausea, vomiting, fever and malaise.
Available controls:
AMPLIRUN® ASTROVIRUS RNA CONTROL (Ref. MBC147-R).
Yersinia enterocolitica
Yersinia enterocolitica is a Gram-negative bacterium of the family Yersiniaceae, responsible for yersiniosis, a gastrointestinal zoonosis. It is transmitted by contact with infected animals or by consumption of contaminated food or water, especially raw or undercooked pork. This bacterium can cause symptoms ranging from mild diarrhoea to appendicitis-like symptoms, and even septicaemia in severe cases. It is most common in children and in temperate regions. It is part of the genus Yersinia, which also includes pathogenic species such as Y. pestis, which causes plague.
Available controls:
AMPLIRUN® YERSINIA ENTEROCOLITICA DNA CONTROL (Ref. MBC027-R)
Shigella flexneri
Shigella flexneri is a species of Gram-negative bacteria of the Enterobacteriaceae family. The main symptom of infection is long-lasting diarrhea, which may include blood. It can also cause fever and stomach pain.
Available controls:
AMPLIRUN® SHIGELLA FLEXNERI DNA CONTROL (Ref.MBC089-R)
AMPLIRUN® TOTAL GASTROINTESTINAL BACTERIAL PANEL CONTROL (STOOL) (Ref. MBTC021)
Vibrio cholerae
Vibrio cholerae is a gram-negative, comma-shaped bacterium found in contaminated water that causes cholera, an acute intestinal infection characterized by intense diarrhea and severe dehydration, which can lead to death.
Available controls:
AMPLIRUN® VIBRIO CHOLERAE DNA CONTROL (Ref. MBC118-R)
Bacillus cereus
Bacillus cereus es una bacteria grampositiva, formadora de esporas, que se encuentra habitualmente en el suelo, el agua y alimentos contaminados. Causa intoxicaciones alimentarias manifestándose con nauseas, vómitos y diarreas.
Available controls:
AMPLIRUN® BACILLUS CEREUS DNA CONTROL (Ref. MBC004-R)
Mycobacterial infections
Mycobacterium tuberculosis
Mycobacterium tuberculosis is the bacterium behind tuberculosis, a contagious airborne disease that primarily targets the lungs but can also affect other organs.
Available controls:
AMPLIRUN® MYCOBACTERIUM AVIUM DNA CONTROL (Ref. MBC086-R)
AMPLIRUN® MYCOBACTERIUM INTRACELLULARE DNA CONTROL (Ref. MBC087-R)
AMPLIRUN® MYCOBACTERIUM KANSASII DNA CONTROL (Ref. MBC095-R)
AMPLIRUN® MYCOBACTERIUM TUBERCULOSIS DNA CONTROL (Ref. MBC034)
AMPLIRUN® MYCOBACTERIUM ULCERANS DNA CONTROL (Ref. MBC094-R)
AMPLIRUN® TOTAL MDR-TB VERIFICATION & CONTROL PANEL (SPUTUM)(Ref. MBTC027)
AMPLIRUN® TOTAL MTB CONTROL (SPUTUM) (Ref. MBTC013)
AMPLIRUN® TOTAL MTB INH RESISTANT (SPUTUM) (Ref. MBTC015)
AMPLIRUN® TOTAL MTB RIF RESISTANT CONTROL (SPUTUM)(Ref. MBTC014)
Nontuberculous mycobacteria (NTM)
Nontuberculous mycobacteria (NTM) are a diverse group of species other than Mycobacterium tuberculosis that can cause chronic pulmonary infections, lymphadenitis, skin and disseminated infections, especially in immunocompromised individuals. Among the most common are M. avium complex, M. abscessus, M. kansasii and M. intracellulare. Their diagnosis is complex and their incidence is increasing, especially in developed countries.
Available controls:
AMPLIRUN® MYCOBACTERIUM AVIUM DNA CONTROL (Ref. MBC086-R)
AMPLIRUN® MYCOBACTERIUM INTRACELLULARE DNA CONTROL (Ref. MBC087-R)
AMPLIRUN® MYCOBACTERIUM KANSASII DNA CONTROL (Ref. MBC095-R)
Mycobacterium ulcerans
Mycobacterium ulcerans is an environmental mycobacterium found mainly in tropical and subtropical areas as well as in aquatic environments. It causes Buruli ulcers, a chronic necrotizing skin disease that can cause permanent deformities, disability and secondary infections.
Available controls:
AMPLIRUN® MYCOBACTERIUM ULCERANS DNA CONTROL (Ref. MBC094-R)
Bacterial respiratory infections
Chlamydophila pneumoniae
Chlamydophila pneumoniae is a respiratory pathogen that causes atypical pneumonia, especially in older adults. These infections are typically mild but may still have clinical significance.
Available controls:
AMPLIRUN® TOTAL ATYPICAL BACTERIAL PNEUMONIA CONTROL (SWAB)(Ref MBTC022-R)
Coxiella burnetii
Coxiella burnetii causes Q fever, a worldwide zoonosis that may present with fever, atypical pneumonia, hepatitis, or endocarditis. Serological diagnosis, especially phase I and II differentiation, is crucial to distinguish acute from chronic infections.
Available controls:
Legionella pneumophila
Legionella pneumophila is a Gram-negative bacterium found in warm water environments. It is the leading cause of Legionnaires' disease and accounts for up to 10% of community- and hospital-acquired pneumonias.
Available controls:
Bordetella
Whooping cough is caused by Bordetella pertussis and B. parapertussis. It is a highly contagious respiratory infection that primarily affects unvaccinated children and spreads through direct contact with respiratory secretions.
Available controls:
Mycoplasma pneumoniae
Mycoplasma pneumoniae is a cell wall-lacking bacterium that causes atypical pneumonia, especially in adolescents and young adults. It is responsible for up to 20% of community-acquired pneumonia cases.
Available controls:
Acinetobacter baumannii
Acinetobacter baumannii is an opportunistic gram-negative bacterium associated with severe nosocomial infections, especially pneumonia, bacteraemia, urinary tract and wound infections. It is notable for its antimicrobial resistance and its ability to persist in hospital settings.
Enterobacter aerogenes
Enterobacter aerogenes is a gram-negative bacterium associated with opportunistic nosocomial infections. It can affect the urinary tract, respiratory tract, surgical wounds or the bloodstream.
Enterobacter cloacae
Enterobacter cloacae is an opportunistic bacterium implicated in hospital-acquired infections, especially bacteraemia, pneumonia and urinary tract infections.
Klebsiella pneumoniae
Klebsiella pneumoniae is a gram-negative bacterium present in the gut microbiota, but potentially pathogenic. It can cause serious infections such as pneumonia, sepsis or urinary tract infections, and is associated with antimicrobial resistance.
Streptococcus pneumoniae
Streptococcus pneumoniae is an encapsulated Gram-positive, immotile, facultative anaerobic coccus, usually occurring in pairs. It is an important respiratory pathogen that can cause otitis, sinusitis, pneumonia, meningitis and sepsis. It is identified by its sensitivity to optokine and solubility in bile. It particularly affects children, the elderly and immunocompromised individuals. Effective vaccines are available for its prevention.
Available controls:
AMPLIRUN® STREPTOCOCCUS PNEUMONIAE DNA CONTROL (Ref. MBC070-R)
Chlamydophila psittaci
Chlamydophila psittaci or Chlamydia psittaci is an obligate intracellular gram-negative bacterium that is transmitted mainly from birds to humans. It causes psittacosis or parrot fever which causes fever, cough and headaches, and can progress to severe pneumonia, hepatitis, endocarditis or encephalitis.
Available controls:
AMPLIRUN® CHLAMYDOPHILA PSITTACI DNA CONTROL (Ref. MBC013-R)
Moraxella catarrhalis
Moraxella catarrhalis is a gram-negative bacterium that can be present without causing disease, although it can become pathogenic in people with low defenses or chronic respiratory diseases. It can cause otitis, sinusitis, acute bronchitis and COPD exacerbations among others.
Available controls:
AMPLIRUN® MORAXELLA CATARRHALIS DNA CONTROL (Ref. MBC117-R)
Corynebacterium diphteriae
Corynebacterium diphtheriae is a Gram-positive, non-spore-forming bacterium that causes diphtheria, an acute upper respiratory infection. It spreads mainly through respiratory droplets from infected individuals or asymptomatic carriers.
The bacterium typically infects the nose and throat, forming a dense, gray-to-black pseudomembrane that may obstruct airways. It produces a diphtheria toxin, which enters the bloodstream and can damage the heart, nervous system, and other organs.
Viral respiratory infections
Adenovirus
Adenoviruses are double-stranded DNA viruses that cause respiratory infections, conjunctivitis, and gastroenteritis. They are highly stable and can survive outside the body for extended periods.
Available controls:
Influenza virus
The influenza virus, responsible for flu, is classified into types A, B, and C and shows high genetic variability. It causes seasonal outbreaks and pandemics, such as H1N1 or H5N1 strains.
Available controls:
Respiratory syncytial virus
Respiratory syncytial virus (RSV) is the leading cause of bronchiolitis and pneumonia in children under 2 years, especially during winter outbreaks. It is a negative-sense single-stranded RNA virus with helical symmetry.
Available controls:
Parainfluenza virus
Parainfluenza viruses (PIV) cause respiratory infections in children such as croup, bronchitis, and pneumonia. Serotype 3 is the second leading cause of pneumonia in infants after RSV.
Available controls:
SARS-CoV-2
SARS-CoV-2 is the coronavirus responsible for the COVID-19 pandemic. It spreads primarily through respiratory droplets and shares high genetic homology with SARS-CoV.
Available controls:
Metapneumovirus
Human metapneumovirus (hMPV) causes mostly mild respiratory infections, but can lead to severe pneumonia in children, the elderly, and immunocompromised individuals.
Available controls:
Rhinovirus
Rhinovirus is an RNA virus belonging to the Picornaviridae family and is the leading cause of the common cold. It is transmitted via respiratory droplets or direct contact with contaminated secretions. Infection is usually mild, presenting with symptoms such as runny nose, sneezing, and general discomfort, but it can exacerbate chronic respiratory conditions. Diagnosis is performed by PCR on respiratory samples.
Available controls:
AMPLIRUN® RHINOVIRUS RNA CONTROL (Ref. MBC091)
MERS Coronavirus
MERS-CoV is a zoonotic coronavirus that causes Middle East Respiratory Syndrome (MERS), a severe respiratory disease with a high mortality rate. It can cause a wide range of symptoms from fever, dry cough, muscle aches, pneumonia, acute respiratory failure to multi-organ failure.
Available controls:
AMPLIRUN® MERS CORONAVIRUS RNA CONTROL (Ref. MBC132-R)
Coronavirus NL63
Coronavirus NL63 (HCoV-NL63) is a human coronavirus that generally causes mild to moderate respiratory infections, which may develop into laryngotracheitis, bronchiolitis or mild pneumonia, especially in children, the elderly and immunocompromised persons.
Available controls:
AMPLIRUN® CORONAVIRUS NL63 RNA CONTROL (Ref. MBC142-R)
Coronavirus OC43
Coronavirus OC43 (HCoV-OC43) is a respiratory virus of the Coronaviridae family, which can cause from mild respiratory infections such as colds or sore throats to bronchitis, pneumonia and exacerbation of chronic respiratory diseases in vulnerable individuals.
Available controls:
AMPLIRUN® CORONAVIRUS OC43 RNA CONTROL (Ref. MBC135-R)
Coronavirus SARS-CoV
The SARS-CoV coronavirus (2003) was the first known coronavirus to cause severe respiratory disease in humans. It causes SARS (Severe Acute Respiratory Syndrome), characterized by fever, malaise, dry cough, respiratory distress, progressive pneumonia and in some cases respiratory failure and death.
Available controls:
AMPLIRUN® CORONAVIRUS SARS (2003) RNA CONTROL (Ref. MBC136-R)
Echovirus
El echovirus (Enteric Cytopathic Human Orphan virus) es un virus ARN que se transmite principalmente por vía fecal-oral. Existen más de 30 serotipos conocidos de echovirus que pueden causar de infecciones leves a enfermedades graves, como meningitis viral, encefalitis, miocarditis, hepatitis neonatal y exantemas virales.
Controles disponibles:
AMPLIRUN® ECHOVIRUS 5 RNA CONTROL (Ref. MBC064-R)
AMPLIRUN® ECHOVIRUS 11 RNA CONTROL (Ref. MBC149-R)
Parvovirus
Parvovirus B19 is a small, non-enveloped, single-stranded DNA virus that belongs to the Parvoviridae family and exclusively infects humans. Parvovirus B19 infection is highly contagious and widespread among children. In most pediatric cases, it presents with mild symptoms including low-grade fever, headache, nasal congestion, and general malaise.
CNS infections
Acanthamoeba
Acanthamoeba is a free-living amoeba that can cause severe keratitis in contact lens users and brain infections in immunocompromised individuals.
Available controls:
Neisseria meningitidis
Neisseria meningitidis, or meningococcus, is a leading cause of bacterial meningitis. It spreads via respiratory droplets in close-contact environments and can lead to severe complications or death.
Available controls:
Enterovirus
Enteroviruses, part of the Picornaviridae family, are small, non-enveloped positive-sense RNA viruses. They cause illnesses ranging from asymptomatic infections to aseptic meningitis, encephalitis, and poliomyelitis. Transmission is fecal-oral or respiratory, mainly affecting children.
Available controls:
Parechovirus
Human parechoviruses (HPeV), from the Picornaviridae family, are small RNA viruses that can cause fever without source, clinical sepsis, meningitis, or encephalitis, mostly in infants.
Available controls:
Streptococcus agalactiae
Streptococcus agalactiae, also known as group B streptococcus (GBS), is part of the gastrointestinal and genital microbiota. In pregnant women, it can be transmitted to the newborn during delivery and cause sepsis, pneumonia or neonatal meningitis. It can also cause urinary tract or invasive infections in immunocompromised adults. Its detection is key in prenatal screening by culture or PCR.
Available controls:
AMPLIRUN® STREPTOCOCCUS AGALACTIAE DNA CONTROL (Ref. MBC071-R)
Cryptococcus neoformans
Cryptococcus neoformans is an encapsulated fungus found in plants and animals. It can cause cryptococcosis, an infection that mainly affects people with weakened immune systems. Its most serious form is cryptococcal meningitis, an infection of the brain that can affect the lungs and other organs.
Available controls:
AMPLIRUN® CRYPTOCOCCUS NEOFORMANS DNA CONTROL (Ref. MBC015-R)
Haemophilus influenzae
Haemophilus influenzae is a gram-negative, coccobacillary, non-motile, facultative aerobic bacterium that can be part of the normal flora of the upper respiratory tract. It can cause bacterial meningitis, epiglottitis, pneumonia and septicemia among other diseases.
Available controls:
AMPLIRUN® HAEMOPHILUS INFLUENZAE DNA CONTROL (Ref. MBC020-R)
Listeria monocytogenes
Listeria monocytogenes is a cold-resistant bacteria found in foods such as unpasteurized dairy products, sausages, smoked fish and poorly washed vegetables. It causes listeriosis infection, which can be especially serious in pregnant women, children and immunocompromised people.
Available controls:
AMPLIRUN® LISTERIA MONOCYTOGENES DNA CONTROL (Ref. MBC033-R)
Streptococcus pneumoniae
Streptococcus pneumoniae is an encapsulated Gram-positive, immotile, facultative anaerobic coccus, usually occurring in pairs. It is an important respiratory pathogen that can cause otitis, sinusitis, pneumonia, meningitis and sepsis. It is identified by its sensitivity to optokine and solubility in bile. It particularly affects children, the elderly and immunocompromised individuals. Effective vaccines are available for its prevention.
Available controls:
AMPLIRUN® STREPTOCOCCUS PNEUMONIAE DNA CONTROL (Ref. MBC070-R)
Coxsackie
Coxsackie is a group of enteroviruses belonging to the Picornaviridae family, which especially infect children and can cause a variety of viral illnesses, mostly self-limiting, although some can be severe.
Available controls:
AMPLIRUN® COXSACKIE B1 RNA CONTROL (Ref. MBC061-R)
AMPLIRUN® COXSACKIE B5 RNA CONTROL (Ref. MBC062-R)
AMPLIRUN® COXSACKIE A6 RNA CONTROL (Ref. MBC063-R)
Echovirus
Echovirus (Enteric Cytopathic Human Orphan virus) is an RNA virus that is mainly transmitted by the fecal-oral route. There are more than 30 known serotypes of echoviruses that can cause mild to severe infections such as viral meningitis, encephalitis, myocarditis, neonatal hepatitis and viral rashes.
Available controls:
AMPLIRUN® ECHOVIRUS 5 RNA CONTROL (Ref. MBC064-R)
AMPLIRUN® ECHOVIRUS 11 RNA CONTROL (Ref. MBC149-R)
Clostridium tetani
Clostridium tetani is a Gram-positive, anaerobic, spore-forming bacterium responsible for tetanus. Its spores are highly resilient and can remain viable in soil for over 40 years. Infection occurs when the spores enter the body through open wounds or cuts, especially in low-oxygen environments, and germinate into active bacteria.
Infectious mononucleosis
Epstein-Barr
Epstein-Barr virus (EBV), part of the Herpesviridae family, causes infectious mononucleosis and is linked to some cancers. It is one of the most common viruses worldwide.
Available controls:
TORCH
Herpes Simplex Virus
Herpes Simplex Virus (HSV), types 1 and 2, is widely prevalent. HSV-1 typically causes oral and ocular infections, while HSV-2 is associated with genital and neonatal infections.
Available controls:
Toxoplasma gondii
Toxoplasma gondii is an intracellular protozoan that can cause severe disease in immunocompromised individuals and fetuses. Transmission occurs via contaminated meat, cat feces, or congenitally.
Available controls:
Cytomegalovirus
Cytomegalovirus (CMV) is a herpesvirus capable of latency after primary infection. It is a major cause of congenital infections and disease in immunocompromised individuals.
Available controls:
Rubella
Rubella is an exanthematous viral disease, contagious but generally mild, whose main medical importance lies in its teratogenic effect when affecting pregnant women, which can cause congenital cataracts, deafness and congenital heart disease.
Available controls:
AMPLIRUN® RUBELLA RNA CONTROL (Ref. MBC113-R)
Zoonotic diseases
Brucella
Brucellosis (Malta Fever) is a zoonotic disease caused by Brucella spp., transmitted to humans through unpasteurized dairy, direct animal contact, or infected aerosols. It can become chronic and persist for years.
Available controls:
Coxiella burnetii
Coxiella burnetii causes Q fever, a worldwide zoonosis that may present with fever, atypical pneumonia, hepatitis, or endocarditis. Serological diagnosis, especially phase I and II differentiation, is crucial to distinguish acute from chronic infections.
Available controls:
Borrelia
Borrelia spp. are motile spirochetes causing Lyme disease. B. burgdorferi sensu lato includes pathogenic species such as B. burgdorferi s.s., B. afzelii, and B. garinii, all found in Europe.
Available controls:
Francisella tularensis
Francisella tularensis, the agent of tularemia, is a highly infectious bacterium transmitted through contact with wild animals, contaminated water, arthropod bites, or aerosol inhalation. Human-to-human transmission does not occur.
Available controls:
Echinococcus granulosus
Echinococcus granulosus is a parasite that causes hydatid disease, leading to cyst formation in organs like the liver and lungs. Symptoms usually appear when cysts grow large and depend on their location
Monkeypox virus
Monkeypox virus is a double-stranded DNA virus with an envelope, from the Orthopoxvirus genus. It is zoonotic, transmitted from rodents or primates to humans, with two main clades: West African and Central African.
Available controls:
AMPLIRUN® TOTAL MONKEYPOX VIRUS CONTROL (SWAB) (Ref. MBTC032-R)
AMPLIRUN® MONKEYPOX VIRUS DNA CONTROL (Ref.MBC146-R)
Ross River virus
Ross River virus is an Alphavirus of the Togaviridae family endemic to Australia, Papua New Guinea and the Solomon Islands. It is transmitted by the bite of Aedes and Culex mosquitoes, with kangaroos and wallabies as the main reservoir. Although up to 30% of cases may be asymptomatic, the infection usually causes fever, arthralgias, rash and fatigue. Diagnosis is made by serology (IgM) or PCR.
Available controls:
AMPLIRUN® ROSS RIVER VIRUS RNA CONTROL (Ref. MBC130-R)
Bartonella
Bartonella is a genus of facultative intracellular gram-negative bacteria that includes species such as B. henselae, the agent of cat scratch disease. It is transmitted by vectors like fleas, lice, or scratches from infected animals, with cats being an important reservoir. Infection can be asymptomatic or cause fever, lymphadenopathy, endocarditis, or bacillary angiomatosis, especially in immunocompromised individuals. Diagnosis is based on serology, specialized culture, or PCR.
Available controls:
AMPLIRUN® BARTONELLA HENSELAE DNA CONTROL (Ref. MBC005-R)
AMPLIRUN® BARTONELLA QUINTANA DNA CONTROL (Ref. MBC006-R)
Leptospira biflexa
Leptospira biflexa is a non-pathogenic spirochete bacterium of the genus Leptospira, widely used as a model to study Leptospira biology and genetics due to its safety and ease of culture.
Available controls:
AMPLIRUN® LEPTOSPIRA BIFLEXA DNA CONTROL (Ref. MBC104-R)
Leptospira interrogans
Leptospira interrogans is the main pathogenic species of the genus. It causes leptospirosis, a zoonotic disease that can present with fever, jaundice, meningitis, renal and/or hepatic failure. It is transmitted by contact with infected animal urine, contaminated water or wet soil.
Urinary tract infections
Acinetobacter baumannii
Acinetobacter baumannii is an opportunistic gram-negative bacterium associated with severe nosocomial infections, especially pneumonia, bacteraemia, urinary tract and wound infections. It is notable for its antimicrobial resistance and its ability to persist in hospital settings.
Enterobacter aerogenes
Enterobacter aerogenes is a gram-negative bacterium associated with opportunistic nosocomial infections. It can affect the urinary tract, respiratory tract, surgical wounds or the bloodstream.
Enterobacter cloacae
Enterobacter cloacae is an opportunistic bacterium implicated in hospital-acquired infections, especially bacteraemia, pneumonia and urinary tract infections
Klebsiella pneumoniae
Klebsiella pneumoniae is a gram-negative bacterium present in the gut microbiota, but potentially pathogenic. It can cause serious infections such as pneumonia, sepsis or urinary tract infections, and is associated with antimicrobial resistance.
Klebsiella oxytoca
Klebsiella oxytoca is a gram-negative bacterium associated with urinary and biliary tract infections. It shares similarities with K. pneumoniae, but differs in specific biochemical characteristics.
Proteus mirabilis
Proteus mirabilis is a gram-negative bacterium implicated in complicated urinary tract infections, especially in the presence of catheters. Its production of urease contributes to the formation of kidney stones.
Proteus vulgaris
Proteus vulgaris is an opportunistic gram-negative bacterium that can cause urinary tract, wound or liver infections, especially in immunocompromised patients.
Proteus penneri
Proteus penneri is a species related to P. mirabilis and P. vulgaris, mainly associated with nosocomial infections of the urinary tract, skin, soft tissues and blood.
Providencia rettgeri
Providencia rettgeri is a gram-negative bacterium found in the environment, associated with urinary tract infections and other opportunistic infections in hospital settings.
Providencia stuartii
Providencia stuartii is an opportunistic pathogen that mainly affects patients with chronic urinary catheters, causing urinary tract infections and sepsis.
Staphylococcus saprophyticus
Staphylococcus saprophyticus is a gram-positive coccus that causes urinary tract infections, especially in young women. It has urease and the ability to adhere to the urogenital epithelium.
Citrobacter freundii
Citrobacter freundii is a Gram-negative bacterium of the Enterobacteriaceae family, present in the environment and in the human intestinal microbiota. It can cause nosocomial infections, especially in immunocompromised patients. Some strains show resistance to multiple antibiotics, such as carbapenemase-producing strains (blaKPC), making it an emerging pathogen in hospitals.
Citrobacter koseri
Citrobacter koseri is a Gram-negative bacterium that is part of the intestinal flora, but can cause opportunistic infections. It is known to be implicated in neonatal meningitis and brain abscesses, as well as urinary tract infections. It mainly affects immunocompromised patients and newborns.
Morganella morganii
Morganella morganii is an opportunistic pathogen that can cause infections mainly in hospitalized or immunocompromised patients. It can cause urinary tract infections, wound and abscess infections, sepsis or bacteremia among others.
Antimicrobial resistance
Staphylococcus aureus
Staphylococcus aureus is a common pathogen in nosocomial infections. It can cause anything from mild skin infections to severe disease such as pneumonia, sepsis or endocarditis.
Available controls:
AMPLIRUN® STAPHYLOCOCCUS AUREUS (mecA-) DNA CONTROL (Ref. MBC073-R)
AMPLIRUN® STAPHYLOCOCCUS AUREUS (mecA-) DNA CONTROL (Ref. MBC074-R)
Klebsiella pneumoniae
Klebsiella pneumoniae is a gram-negative bacterium present in the gut microbiota, but potentially pathogenic. It can cause serious infections such as pneumonia, sepsis or urinary tract infections, and is associated with antimicrobial resistance.
Available controls:
AMPLIRUN® KLEBSIELLA PNEUMONIAE (NDM-1) DNA CONTROL (Ref. MBC107-R)
Enterococcus faecalis
Enterococcus faecalis is a Gram-positive bacterium that is part of the human gut microbiota. Although normally commensal, it can cause serious opportunistic infections in hospital settings, such as endocarditis, urinary tract infections and bacteraemias. Its clinical importance lies in its ability to acquire resistance to multiple antibiotics, including vancomycin, which complicates its treatment.
Available controls:
AMPLIRUN® ENTEROCOCCUS FAECALIS (vanB) DNA CONTROL (Ref. MBC115-R)
Enterococcus faecium
Enterococcus faecium is a Gram-positive bacterium, usually commensal to the gut, but capable of causing serious infections in immunocompromised patients, such as neonatal meningitis or nosocomial infections. Like E. faecalis, it has developed resistance to several antibiotics, including vancomycin (VRE), which presents a challenge in hospitals.
Available controls:
AMPLIRUN® ENTEROCOCCUS FAECIUM (vanA) DNA CONTROL (Ref. MBC116-R)
Other infections
Hepatitis Delta
Hepatitis delta virus (HDV) is a defective virus that requires hepatitis B virus (HBV) to replicate. It can worsen existing HBV infections and lead to chronic disease with symptoms resembling hepatitis B.
Hepatitis E
Hepatitis E virus (HEV) is mainly transmitted via the fecal-oral route or through contaminated food. It poses a particular risk to immunocompromised individuals and pregnant women, and is increasingly recognized in clinical settings.
Staphylococcus epidermidis
Staphylococcus epidermidis is a skin commensal involved in nosocomial infections due to biofilm formation on medical devices. It is multidrug-resistant and causes sepsis, endocarditis and other infections.
Acanthamoeba castellanii
Acanthamoeba castellanii is a free-living protozoan found in water, air and soil. It can cause human diseases such as amoebic keratitis, especially in contact lens wearers, and granulomatous amoebic encephalitis, a rare but fatal infection in immunocompromised patients. Its life cycle includes trophozoite and cystic forms, allowing it to survive in adverse conditions.
Available controls:
AMPLIRUN® ACANTHAMOEBA CASTELLANII DNA CONTROL (Ref. MBC054-R)
BK virus
BK virus is a human polyomavirus that infects most people in childhood and remains latent in the body. It can reactivate in people with weakened immune systems causing serious complications, such as inflammation and damage of the kidney graft or hemorrhagic cystitis.
Available controls:
AMPLIRUN® BK VIRUS DNA CONTROL (Ref. MBC051-R)
Abiotrophia defectiva
Abiotrophia defectiva is a gram-positive bacterium that is part of the normal microbiota of the oral cavity, gastrointestinal and genitourinary tract, but can cause serious infections under special conditions, such as infective endocarditis.
Pseudomonas aeruginosa
Pseudomonas aeruginosa is an opportunistic gram-negative bacterium, widely distributed in the environment that can cause serious infections in immunocompromised individuals.
Serratia marcescens
Serratia marcescens is an opportunistic gram-negative bacterium belonging to the Enterobacteriaceae family that can cause nosocomial infections especially in immunocompromised individuals or those with invasive medical devices.
JC virus
JC virus is a human polyomavirus that infects most people at some point in their lives, usually during childhood. In healthy individuals, it usually remains latent, but can reactivate in immunocompromised individuals causing Progressive Multifocal Leukoencephalopathy (PML), a severe and potentially fatal brain disease.
Available controls:
AMPLIRUN® JC VIRUS DNA CONTROL (Ref. MBC150-R)
Chlamydia trachomatis is an intracellular bacterium responsible for one of the most prevalent sexually transmitted infections, linked to urethritis, cervicitis, neonatal conjunctivitis, and trachoma.
Available controls:
Treponema pallidum is a spirochete bacterium that causes syphilis, a sexually transmitted disease with multiple stages that may result in systemic damage if untreated.
Available controls:
HPV is a DNA virus that infects epithelial tissues, causing common and genital warts as well as cervical precancerous lesions linked to high-risk genotypes.
Available controls:
Trichomonas vaginalis is a sexually transmitted protozoan parasite that commonly affects women, leading to abnormal discharge, irritation, and genital discomfort.
Available controls:
Neisseria gonorrhoeae is a Gram-negative bacterium responsible for gonorrhea, a common STI that can lead to pelvic inflammatory disease and infertility if untreated.
Available controls:
Gardnerella vaginalis is associated with bacterial vaginosis, a condition resulting from an imbalance in the vaginal microbiota, linked to increased risk of STIs and obstetric complications.
Available controls:
Atopobium vaginae is frequently found in women with bacterial vaginosis (BV), a common vaginal infection. It can cause symptoms like discharge, irritation, or odor, though many cases are asymptomatic. Diagnosis is more reliable using molecular techniques like multiplex PCR.
Ureaplasma parvum is a bacterium of the genus Ureaplasma and family Mycoplasmataceae, which is part of the normal genital microbiota, but can behave as a pathogen. It is associated with urethritis, vaginitis, pelvic inflammatory disease, infertility and pregnancy complications. It can also affect the newborn, causing sepsis or meningitis. It is detected by PCR or specialised culture.
Available controls:
AMPLIRUN® UREAPLASMA PARVUM DNA CONTROL (Ref. MBC133-R)
Ureaplasma urealyticum is a bacterium of the genus Ureaplasma and of the family Mycoplasmataceae, characterised by the absence of a cell wall. It colonises the urogenital tract of a large percentage of healthy adults, especially women, where it can behave as a commensal. However, under certain circumstances, it can act as an opportunistic pathogen associated with urethritis, vaginitis, chorioamnionitis, premature delivery and neonatal complications. Infection is sexually transmitted and diagnosis is by specialised culture or molecular techniques such as PCR.
Available controls:
AMPLIRUN® UREAPLASMA UREALYTICUM DNA CONTROL (MBC112)
Mycoplasma hominis is a cell wall–lacking bacterium belonging to the family Mycoplasmataceae that colonizes the human genitourinary tract. It is primarily transmitted through sexual contact and can cause urinary infections, vaginitis, and pregnancy complications. Although many infections are asymptomatic, it can cause fever, pelvic pain, and vaginal discharge. Diagnosis is performed through specific culture or PCR.
Available controls:
AMPLIRUN® MYCOPLASMA HOMINIS DNA CONTROL (Ref. MBC084)
Mycoplasma genitalium is a cell wall–lacking bacterium that colonizes the human urogenital tract and is primarily transmitted through sexual contact. It is associated with nongonococcal urethritis, cervicitis, and pelvic inflammatory disease. Many infections can be asymptomatic but may also cause pain during urination, discharge, and pelvic discomfort. Diagnosis is performed by PCR due to the difficulty of culturing the organism.
Available controls:
AMPLIRUN® MYCOPLASMA GENITALIUM DNA CONTROL (Ref. MBC085)
AMPLIRUN® TOTAL MACROLIDE RESISTANT MGE CONTROL PANEL (SWAB) (Ref. MBTC029)
Haemophilus ducreyi is a gram-negative bacterium that causes chancroid, a sexually transmitted infection that is uncommon in developed countries. It presents with painful genital ulcers and inguinal lymphadenopathy. It mainly affects sexually active individuals in tropical and subtropical regions. Diagnosis is based on clinical presentation, culture, or PCR.
Available controls:
AMPLIRUN® HAEMOPHILUS DUCREYI DNA CONTROL (Ref. MBC021-R)
Herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) are DNA viruses from the Herpesviridae family that cause recurrent mucocutaneous infections. HSV-1 is commonly associated with oral herpes, while HSV-2 is more frequently linked to genital herpes. Infection may be asymptomatic or present with painful vesicular lesions. Diagnosis is made by PCR or serology.
Available controls:
AMPLIRUN® HERPES SIMPLEX 1 DNA CONTROL (Ref. MBC023)
AMPLIRUN® HERPES SIMPLEX 2 DNA CONTROL (Ref. MBC024)
Gardnerella vaginalis is a gram-variable bacterium that is part of the normal vaginal microbiota in small amounts. Its overgrowth is associated with bacterial vaginosis (BV), a common vaginal infection in women of childbearing age.
Available controls:
AMPLIRUN® GARDNERELLA VAGINALIS DNA CONTROL (Ref. MBC108-R)
Macrolide resistant MGE refers to mobile genetic elements that carry genes for resistance to macrolides, an important class of antibiotics. It is not a specific organism, but a mechanism of dissemination of antimicrobial resistance. They usually carry bacteria such as Streptococcus pneumoniae, Staphylococcus aureus, Enterococcus spp, Mycoplasma genitalium or Campylobacter spp.
Available controls:
AMPLIRUN® TOTAL MACROLIDE RESISTANT MGE CONTROL PANEL (SWAB) (Ref. MBTC029)
Chagas disease is caused by Trypanosoma cruzi, a parasite mainly transmitted by triatomine insects in Latin America. It can also spread via blood transfusion, congenital transmission, or lab exposure.
Available controls:
Dengue virus is mosquito-borne (Aedes spp.) and among the fastest-spreading viral diseases worldwide, with millions of cases yearly in tropical and subtropical regions.
Available controls:
Zika virus is a flavivirus transmitted by Aedes mosquitoes that may cause mild symptoms, but can also lead to neurological issues and congenital microcephaly in newborns.
Available controls:
West Nile virus is an emerging mosquito-borne flavivirus that may cause mild illness or serious neuroinvasive disease in humans. It has a wide global distribution.
Available controls:
Toscana virus is a Phlebovirus transmitted by sandflies, associated with seasonal viral meningitis in Mediterranean countries of southern Europe.
Available controls:
Chikungunya virus is an RNA virus of the genus Alphavirus, transmitted by Aedes aegypti and Aedes albopictus mosquitoes. It causes sudden fever, severe joint pain, rash, nausea and fatigue. It is generally not fatal, but can cause complications in infants and vulnerable people. Diagnosis is made by molecular or serological tests. There is no vaccine or specific treatment; rest, analgesics and good hydration are indicated.
Available controls:
AMPLIRUN® CHIKUNGUNYA VIRUS RNA CONTROL (Ref. MBC099-R)
AMPLIRUN® TOTAL ZIKV/DENV/CHIKV CONTROL (PLASMA) (Ref. MBTC023)
Japanese encephalitis virus belongs to the genus Flavivirus and is transmitted by mosquitoes of the genus Culex. The main reservoirs are pigs and waterfowl. Most infections are asymptomatic, but in some cases it can cause encephalitis with fever, headache, convulsions and neurological disturbances. There is no specific treatment; prevention is based on vaccination and vector control.
Available controls:
AMPLIRUN® JAPANESE ENCEPHALITIS RNA CONTROL (Ref. MBC134-R).
Plasmodium is a genus of apicomplexan protists responsible for malaria. It is transmitted by the bite of mosquitoes of the genus Anopheles. In humans, the most relevant species are P. falciparum, P. vivax, P. ovale and P. malariae. The life cycle includes hepatic and erythrocytic phases, and infection can range from mild febrile to severe forms with anaemia, coma or death. Diagnosis is made by microscopy or rapid antigen tests.
Available controls:
AMPLIRUN® PLASMODIUM FALCIPARUM DNA CONTROL (Ref. MBC148-R)
Mayaro disease is a viral infection belonging to the genus Alphavirus, transmitted by mosquitoes. It causes fever, rash, headache and joint pain. It is found mainly in jungle and rural areas of South America and is considered endemic in tropical forests.
Available controls:
AMPLIRUN® MAYARO VIRUS RNA CONTROL (Rf. MBC153-R)
Oropouche syndrome is a viral disease endemic in some areas of Latin America and the Caribbean. It is transmitted by insects and presents flu-like symptoms such as fever, headache, muscle and joint pain, including nausea and vomiting.
Available controls:
AMPLIRUN® OROPOUCHE VIRUS RNA CONTROL (Ref. MBC152-R)
Ross River virus, transmitted by different species of mosquitoes, is endemic in Australia, Papua New Guinea and Solomon Islands, the main reservoirs being kangaroos and wallabies. It usually causes arthralgias, fever, headache, skin lesions and fatigue.
Available controls:
AMPLIRUN® ROSS RIVER VIRUS RNA CONTROL (Ref. MBC130-R)
Tick-borne encephalitis is a viral disease caused by a virus, an arbovirus of the genus Flavivirus, which affects the central nervous system. It is endemic in certain areas of Central and Eastern Europe and parts of Asia.
Available controls:
AMPLIRUN® TICK-BORNE ENCEPHALITIS VIRUS RNA CONTROL (Ref. MBC045-R)
Leishmania infantum is a protozoan parasite of the genus Leishmania that is transmitted to humans and animals (essentially dogs) through mosquito bites. It can cause the most deadly variant of leishmaniasis in humans.
Available controls:
AMPLIRUN® LEISHMANIA INFANTUM DNA CONTROL (Ref. MBC032-R)
Leishmania chagasi also known as leishmania infantum is a zoonosis, with dogs being the main reservoir. It can cause prolonged fever, weight loss, enlargement of the spleen or liver and anemia in humans.
Available controls:
AMPLIRUN® LEISHMANIA CHAGASI DNA CONTROL (Ref. MBC060-R)
Venezuelan Equine Encephalitis is a zoonotic viral disease caused by Venezuelan equine encephalitis virus, an alphavirus of the Togaviridae family. It usually presents a mild picture in humans but progresses to encephalitis.
Available controls:
AMPLIRUN® VENEZUELAN EQUINE ENCEPHALITIS VIRUS RNA CONTROL (Ref. MBC096-R)
Eastern Equine Encephalitis is a severe viral disease caused by a mosquito-borne alphavirus that affects equines and humans. Although rare in humans, it can cause severe encephalitis with a high mortality rate.
Available controls:
AMPLIRUN® EASTERN EQUINE ENCEPHALITIS RNA CONTROL (Ref. MBC097-R)
Yellow fever is an acute viral and hemorrhagic disease caused by a mosquito-borne flavivirus. It causes muscle pain, vomiting, headache and fever in its acute phase, and may progress to jaundice, hemorrhages and liver and kidney damage in its toxic phase, with high mortality.
Available controls:
AMPLIRUN® YELLOW FEVER VIRUS RNA CONTROL (Ref. MBC100-R)
St. Louis encephalitis is a viral disease of the central nervous system caused by a mosquito-borne flavivirus. It causes viral encephalitis that can lead to coma and/or permanent damage and even death in severe cases.
Available controls:
AMPLIRUN® ST LOUIS ENCEPHALITIS VIRUS RNA CONTROL (Ref. MBC101-R)
Orientia tsutsugamushi is an obligate intracellular bacterium that causes the disease called Tsutsugamushi or scrub typhus fever. It is transmitted by the bite of infected trombiculine mite larvae and causes sudden high fever, severe headache, joint muscle pain and rash among others.
Available controls:
AMPLIRUN® ORIENTIA TSUTSUGAMUSHI DNA CONTROL (Ref. MBC106-R)
Rickettsia conorii is an obligate intracellular Gram-negative bacterium of the Rickettsiaceae family. It is the causative agent of Mediterranean spotted fever, a tick-borne infectious disease endemic to Mediterranean countries, with seasonal peaks during spring and summer. The disease is transmitted to humans through the bite of infected ticks, mainly of the Rhipicephalus genus.
Measles is a highly contagious viral illness primarily affecting children. Despite widespread vaccination, outbreaks continue to appear, especially in under-immunized populations. Severe complications include encephalitis and subacute sclerosing panencephalitis.
Available controls:
The mumps virus causes swelling of the parotid salivary glands and is a leading cause of aseptic meningitis. It can also result in complications like orchitis, pancreatitis, or ovarian inflammation.
Available controls:
Varicella-Zoster Virus (VZV) is a herpesvirus responsible for chickenpox and shingles. After primary infection, the virus remains dormant in the body and may reactivate later in life.
Available controls:
Rubella is an exanthematous viral disease, contagious but generally mild, whose main medical importance lies in its teratogenic effect when affecting pregnant women, which can cause congenital cataracts, deafness and congenital heart disease.
Available controls:
AMPLIRUN® RUBELLA RNA CONTROL (Ref. MBC113-R)
Candida albicans is an opportunistic yeast that can cause anything from superficial infections to severe invasive candidiasis, especially in immunocompromised patients. It commonly colonizes the skin, vagina, and gastrointestinal tract.
Available controls:
Aspergillus fumigatus is an airborne fungus capable of triggering respiratory conditions ranging from allergic reactions to invasive aspergillosis in immunocompromised hosts. It is widespread in the environment.
Available controls:
Pneumocystis jirovecii is an opportunistic fungus that causes severe pneumonia (PcP) in immunocompromised patients. It cannot be cultured and is diagnosed using molecular or immunofluorescence-based techniques.
Candida auris is a fungus that can cause a serious infection in the bloodstream and organs. It usually affects people who already have another disease, so its diagnosis is complicated by the fact that it is difficult to distinguish its symptoms from those of other infections.
Available controls:
AMPLIRUN® CANDIDA AURIS DNA CONTROL (Ref. MBC127-R)
Cryptococcus neoformans is an encapsulated fungus found in plants and animals. It can cause cryptococcosis, an infection that mainly affects people with weakened immune systems. Its most serious form is cryptococcal meningitis, an infection of the brain that can affect the lungs and other organs.
Available controls:
AMPLIRUN® CRYPTOCOCCUS NEOFORMANS DNA CONTROL (Ref. MBC015-R)
Aspergillus flavus is an opportunistic fungus of the genus Aspergillus, widely distributed in nature that can contaminate food with substances and cause diseases such as invasive aspergillosis or fungal otitis externa among others.
Aspergillus niger is a fungus of the genus Aspergillus common in the environment. It can cause otomycosis, pulmonary aspergillosis (rarely invasive) and chronic fungal sinusitis.
Aspergillus terreus is a filamentous fungus of the genus Aspergillus found in soil, dust and decaying plant matter. It can cause invasive pulmonary aspergillosis and spread to other organs, especially in immunocompromised individuals.
Helicobacter pylori is a stomach-infecting bacterium linked to gastritis, gastric and duodenal ulcers, and increased risk of gastric cancer. It is more common in developing countries.
Available controls:
Clostridioides difficile is a bacterium that causes intestinal infections, especially in hospital settings after antibiotic use. It’s the most common cause of healthcare-associated diarrhea, with severity ranging from mild cases to pseudomembranous colitis. Diagnosis involves antigen/toxin detection or molecular tests like PCR.
Available controls:
AMPLIRUN® CLOSTRIDIUM DIFFICILE DNA CONTROL (Ref. MBC043-R)
AMPLIRUN® TOTAL CLOSTRIDIUM DIFFICILE RT027 CONTROL (STOOL) (Ref. MBTC026-R)
AMPLIRUN® TOTAL GASTROINTESTINAL BACTERIAL PANEL CONTROL (STOOL) (Ref. MBTC021)
👉 Learn more about Clostridioides difficile at Vircell
E. coli is a Gram-negative bacterium common in the human gut. Although many strains are harmless, some are pathogenic and cause diarrhoea, urinary tract infections or septicaemia. The most important variants include: EPEC, ETEC, EHEC, EIEC and EAEC. Shiga toxin-producing strains (STEC/EHEC) can trigger severe conditions such as haemorrhagic colitis and haemolytic uraemic syndrome (HUS).
Available controls:
AMPLIRUN® ESCHERICHIA COLI (EAEC) DNA CONTROL (Ref. MBC121-R)
AMPLIRUN® ESCHERICHIA COLI (EIEC) DNA CONTROL (Ref. MBC122-R)
AMPLIRUN® ESCHERICHIA COLI (EPEC) DNA CONTROL (Ref. MBC123-R)
AMPLIRUN® ESCHERICHIA COLI (ETEC) DNA CONTROL (Ref. MBC124-R)
AMPLIRUN® TOTAL GASTROINTESTINAL BACTERIAL PANEL CONTROL (STOOL) (MBTC021)
AMPLIRUN® ESCHERICHIA COLI (VTEC) DNA CONTROL (Ref. MBC022-R)
Norovirus is a highly contagious RNA virus that causes outbreaks of acute gastroenteritis with vomiting, diarrhoea and abdominal pain. It is easily transmitted by contaminated food or water, person-to-person contact or infected surfaces. It is a leading cause of viral gastroenteritis worldwide, affecting people of all ages, especially in closed environments.
Available controls:
AMPLIRUN® NOROVIRUS RNA CONTROL (Ref. MBC111-R)
Rotavirus is a double-stranded RNA virus that causes severe diarrhoea in children under 5 years of age and animal neonates. It is transmitted by the faecal-oral route and has a high morbidity in developing countries. Almost all children have had a rotavirus infection before the age of 5 years. In animals, such as calves, it can cause neonatal diarrhoea, leading to economic losses in animal husbandry.
Available controls:
AMPLIRUN® ROTAVIRUS RNA CONTROL (Ref. MBC026-R)
Adenoviruses are non-enveloped DNA viruses that can infect both humans and animals. They cause respiratory infections, gastroenteritis, conjunctivitis and haemorrhagic cystitis. Their ability to remain in the environment and their high transmissibility make them relevant in outbreaks. In addition, they are used as vectors in gene therapies and vaccines because of their efficiency in gene transfer.
Available controls:
AMPLIRUN® ADENOVIRUS DNA CONTROL (Ref. MBC001)
AMPLIRUN® ADENOVIRUS 41 DNA CONTROL (Ref. MBC114-R)
Sapovirus is an RNA virus of the genus Caliciviridae that causes acute gastroenteritis, mainly in children. Together with norovirus, it is a major cause of outbreaks of viral diarrhoea. It is transmitted by faecal-oral route, contaminated food or close contact. It causes watery diarrhoea, nausea and vomiting, with symptoms usually resolving within a few days.
Available controls:
AMPLIRUN® SAPOVIRUS RNA CONTROL (Ref. MBC151-R)
Salmonella is a genus of Gram-negative, flagellated, facultative anaerobic bacteria. It is found in animals and humans, and can cause salmonellosis, a gastrointestinal infection through consumption of contaminated food, especially meat or eggs. S. enterica is the most pathogenic species, and in some cases can invade the bloodstream and cause systemic illness.
Available controls:
AMPLIRUN® SALMONELLA ENTERITIDIS DNA CONTROL (Ref. MBC003-R)
AMPLIRUN® SALMONELLA TYPHI DNA CONTROL (Ref. MBC044-R)
Entamoeba histolytica is a parasitic protozoan responsible for amoebiasis, an intestinal disease also known as amoebic dysentery. It is transmitted mainly by ingestion of food or water contaminated with cysts of the parasite, which can survive in the environment. In most cases, the infection is asymptomatic, but can cause symptoms such as diarrhoea, abdominal pain, colitis and, in more severe cases, dysentery or liver abscesses.
Giardia lamblia, also known as G. intestinalis or G. duodenalis, is a flagellate protozoan that inhabits the small intestine of humans and other mammals. It is the causative agent of giardiasis, an intestinal disease characterised by watery diarrhoea, malabsorption and abdominal pain. It is transmitted mainly by the faecal-oral route, through contaminated food or water.
Available controls:
AMPLIRUN® GIARDIA INTESTINALIS DNA CONTROL (Ref. MBC119-R)
Cryptosporidium is a genus of apicomplexan protists that causes cryptosporidiosis, a faecal-oral diarrhoeal disease. Unlike other apicomplexans such as Plasmodium or Toxoplasma, Cryptosporidium does not require vectors and completes its life cycle in a single host. It is transmitted by ingestion of resistant oocysts present in contaminated food or water. In healthy people, it usually causes self-limiting diarrhoea, but in young or immunocompromised children it can cause prolonged or severe infections. The most common species in humans are C. hominis and C. parvum.
Available controls:
AMPLIRUN® CRYPTOSPORIDIUM PARVUM DNA CONTROL (Ref. MBC126-R)
Campylobacter is a genus of Gram-negative, spiral-shaped bacteria, considered a major cause of gastroenteritis worldwide. The most common species is Campylobacter jejuni, although C. coli, C. lari and others have also been implicated. Infection is mainly acquired through consumption of contaminated food. Symptoms include diarrhoea, fever, abdominal pain and, in rare cases, complications such as Guillain-Barré syndrome. Campylobacteriosis is especially common and severe in young children and immunocompromised persons.
Available controls:
AMPLIRUN® TOTAL GASTROINTESTINAL BACTERIAL PANEL CONTROL (STOOL) (Ref. MBTC021).
AMPLIRUN® CAMPYLOBACTER JEJUNI DNA CONTROL (Ref. MBC088-R)
Astroviruses are non-enveloped single-stranded positive RNA viruses belonging to the family Astroviridae. They are a common cause of viral gastroenteritis, especially in children, the elderly and immunocompromised individuals. Infection produces mild to moderate symptoms such as diarrhoea, nausea, vomiting, fever and malaise.
Available controls:
AMPLIRUN® ASTROVIRUS RNA CONTROL (Ref. MBC147-R).
Yersinia enterocolitica is a Gram-negative bacterium of the family Yersiniaceae, responsible for yersiniosis, a gastrointestinal zoonosis. It is transmitted by contact with infected animals or by consumption of contaminated food or water, especially raw or undercooked pork. This bacterium can cause symptoms ranging from mild diarrhoea to appendicitis-like symptoms, and even septicaemia in severe cases. It is most common in children and in temperate regions. It is part of the genus Yersinia, which also includes pathogenic species such as Y. pestis, which causes plague.
Available controls:
AMPLIRUN® YERSINIA ENTEROCOLITICA DNA CONTROL (Ref. MBC027-R)
Shigella flexneri is a species of Gram-negative bacteria of the Enterobacteriaceae family. The main symptom of infection is long-lasting diarrhea, which may include blood. It can also cause fever and stomach pain.
Available controls:
AMPLIRUN® SHIGELLA FLEXNERI DNA CONTROL (Ref.MBC089-R)
AMPLIRUN® TOTAL GASTROINTESTINAL BACTERIAL PANEL CONTROL (STOOL) (Ref. MBTC021)
Vibrio cholerae is a gram-negative, comma-shaped bacterium found in contaminated water that causes cholera, an acute intestinal infection characterized by intense diarrhea and severe dehydration, which can lead to death.
Available controls:
AMPLIRUN® VIBRIO CHOLERAE DNA CONTROL (Ref. MBC118-R)
Bacillus cereus es una bacteria grampositiva, formadora de esporas, que se encuentra habitualmente en el suelo, el agua y alimentos contaminados. Causa intoxicaciones alimentarias manifestándose con nauseas, vómitos y diarreas.
Available controls:
AMPLIRUN® BACILLUS CEREUS DNA CONTROL (Ref. MBC004-R)
Mycobacterium tuberculosis is the bacterium behind tuberculosis, a contagious airborne disease that primarily targets the lungs but can also affect other organs.
Available controls:
AMPLIRUN® MYCOBACTERIUM AVIUM DNA CONTROL (Ref. MBC086-R)
AMPLIRUN® MYCOBACTERIUM INTRACELLULARE DNA CONTROL (Ref. MBC087-R)
AMPLIRUN® MYCOBACTERIUM KANSASII DNA CONTROL (Ref. MBC095-R)
AMPLIRUN® MYCOBACTERIUM TUBERCULOSIS DNA CONTROL (Ref. MBC034)
AMPLIRUN® MYCOBACTERIUM ULCERANS DNA CONTROL (Ref. MBC094-R)
AMPLIRUN® TOTAL MDR-TB VERIFICATION & CONTROL PANEL (SPUTUM)(Ref. MBTC027)
AMPLIRUN® TOTAL MTB CONTROL (SPUTUM) (Ref. MBTC013)
AMPLIRUN® TOTAL MTB INH RESISTANT (SPUTUM) (Ref. MBTC015)
AMPLIRUN® TOTAL MTB RIF RESISTANT CONTROL (SPUTUM)(Ref. MBTC014)
Nontuberculous mycobacteria (NTM) are a diverse group of species other than Mycobacterium tuberculosis that can cause chronic pulmonary infections, lymphadenitis, skin and disseminated infections, especially in immunocompromised individuals. Among the most common are M. avium complex, M. abscessus, M. kansasii and M. intracellulare. Their diagnosis is complex and their incidence is increasing, especially in developed countries.
Available controls:
AMPLIRUN® MYCOBACTERIUM AVIUM DNA CONTROL (Ref. MBC086-R)
AMPLIRUN® MYCOBACTERIUM INTRACELLULARE DNA CONTROL (Ref. MBC087-R)
AMPLIRUN® MYCOBACTERIUM KANSASII DNA CONTROL (Ref. MBC095-R)
Mycobacterium ulcerans is an environmental mycobacterium found mainly in tropical and subtropical areas as well as in aquatic environments. It causes Buruli ulcers, a chronic necrotizing skin disease that can cause permanent deformities, disability and secondary infections.
Available controls:
AMPLIRUN® MYCOBACTERIUM ULCERANS DNA CONTROL (Ref. MBC094-R)
Chlamydophila pneumoniae is a respiratory pathogen that causes atypical pneumonia, especially in older adults. These infections are typically mild but may still have clinical significance.
Available controls:
AMPLIRUN® TOTAL ATYPICAL BACTERIAL PNEUMONIA CONTROL (SWAB)(Ref MBTC022-R)
Coxiella burnetii causes Q fever, a worldwide zoonosis that may present with fever, atypical pneumonia, hepatitis, or endocarditis. Serological diagnosis, especially phase I and II differentiation, is crucial to distinguish acute from chronic infections.
Available controls:
Legionella pneumophila is a Gram-negative bacterium found in warm water environments. It is the leading cause of Legionnaires' disease and accounts for up to 10% of community- and hospital-acquired pneumonias.
Available controls:
Whooping cough is caused by Bordetella pertussis and B. parapertussis. It is a highly contagious respiratory infection that primarily affects unvaccinated children and spreads through direct contact with respiratory secretions.
Available controls:
Mycoplasma pneumoniae is a cell wall-lacking bacterium that causes atypical pneumonia, especially in adolescents and young adults. It is responsible for up to 20% of community-acquired pneumonia cases.
Available controls:
Acinetobacter baumannii is an opportunistic gram-negative bacterium associated with severe nosocomial infections, especially pneumonia, bacteraemia, urinary tract and wound infections. It is notable for its antimicrobial resistance and its ability to persist in hospital settings.
Enterobacter aerogenes is a gram-negative bacterium associated with opportunistic nosocomial infections. It can affect the urinary tract, respiratory tract, surgical wounds or the bloodstream.
Enterobacter cloacae is an opportunistic bacterium implicated in hospital-acquired infections, especially bacteraemia, pneumonia and urinary tract infections.
Klebsiella pneumoniae is a gram-negative bacterium present in the gut microbiota, but potentially pathogenic. It can cause serious infections such as pneumonia, sepsis or urinary tract infections, and is associated with antimicrobial resistance.
Streptococcus pneumoniae is an encapsulated Gram-positive, immotile, facultative anaerobic coccus, usually occurring in pairs. It is an important respiratory pathogen that can cause otitis, sinusitis, pneumonia, meningitis and sepsis. It is identified by its sensitivity to optokine and solubility in bile. It particularly affects children, the elderly and immunocompromised individuals. Effective vaccines are available for its prevention.
Available controls:
AMPLIRUN® STREPTOCOCCUS PNEUMONIAE DNA CONTROL (Ref. MBC070-R)
Chlamydophila psittaci or Chlamydia psittaci is an obligate intracellular gram-negative bacterium that is transmitted mainly from birds to humans. It causes psittacosis or parrot fever which causes fever, cough and headaches, and can progress to severe pneumonia, hepatitis, endocarditis or encephalitis.
Available controls:
AMPLIRUN® CHLAMYDOPHILA PSITTACI DNA CONTROL (Ref. MBC013-R)
Moraxella catarrhalis is a gram-negative bacterium that can be present without causing disease, although it can become pathogenic in people with low defenses or chronic respiratory diseases. It can cause otitis, sinusitis, acute bronchitis and COPD exacerbations among others.
Available controls:
AMPLIRUN® MORAXELLA CATARRHALIS DNA CONTROL (Ref. MBC117-R)
Corynebacterium diphtheriae is a Gram-positive, non-spore-forming bacterium that causes diphtheria, an acute upper respiratory infection. It spreads mainly through respiratory droplets from infected individuals or asymptomatic carriers.
The bacterium typically infects the nose and throat, forming a dense, gray-to-black pseudomembrane that may obstruct airways. It produces a diphtheria toxin, which enters the bloodstream and can damage the heart, nervous system, and other organs.
Adenoviruses are double-stranded DNA viruses that cause respiratory infections, conjunctivitis, and gastroenteritis. They are highly stable and can survive outside the body for extended periods.
Available controls:
The influenza virus, responsible for flu, is classified into types A, B, and C and shows high genetic variability. It causes seasonal outbreaks and pandemics, such as H1N1 or H5N1 strains.
Available controls:
Respiratory syncytial virus (RSV) is the leading cause of bronchiolitis and pneumonia in children under 2 years, especially during winter outbreaks. It is a negative-sense single-stranded RNA virus with helical symmetry.
Available controls:
Parainfluenza viruses (PIV) cause respiratory infections in children such as croup, bronchitis, and pneumonia. Serotype 3 is the second leading cause of pneumonia in infants after RSV.
Available controls:
SARS-CoV-2 is the coronavirus responsible for the COVID-19 pandemic. It spreads primarily through respiratory droplets and shares high genetic homology with SARS-CoV.
Available controls:
Human metapneumovirus (hMPV) causes mostly mild respiratory infections, but can lead to severe pneumonia in children, the elderly, and immunocompromised individuals.
Available controls:
Rhinovirus is an RNA virus belonging to the Picornaviridae family and is the leading cause of the common cold. It is transmitted via respiratory droplets or direct contact with contaminated secretions. Infection is usually mild, presenting with symptoms such as runny nose, sneezing, and general discomfort, but it can exacerbate chronic respiratory conditions. Diagnosis is performed by PCR on respiratory samples.
Available controls:
AMPLIRUN® RHINOVIRUS RNA CONTROL (Ref. MBC091)
MERS-CoV is a zoonotic coronavirus that causes Middle East Respiratory Syndrome (MERS), a severe respiratory disease with a high mortality rate. It can cause a wide range of symptoms from fever, dry cough, muscle aches, pneumonia, acute respiratory failure to multi-organ failure.
Available controls:
AMPLIRUN® MERS CORONAVIRUS RNA CONTROL (Ref. MBC132-R)
Coronavirus NL63 (HCoV-NL63) is a human coronavirus that generally causes mild to moderate respiratory infections, which may develop into laryngotracheitis, bronchiolitis or mild pneumonia, especially in children, the elderly and immunocompromised persons.
Available controls:
AMPLIRUN® CORONAVIRUS NL63 RNA CONTROL (Ref. MBC142-R)
Coronavirus OC43 (HCoV-OC43) is a respiratory virus of the Coronaviridae family, which can cause from mild respiratory infections such as colds or sore throats to bronchitis, pneumonia and exacerbation of chronic respiratory diseases in vulnerable individuals.
Available controls:
AMPLIRUN® CORONAVIRUS OC43 RNA CONTROL (Ref. MBC135-R)
The SARS-CoV coronavirus (2003) was the first known coronavirus to cause severe respiratory disease in humans. It causes SARS (Severe Acute Respiratory Syndrome), characterized by fever, malaise, dry cough, respiratory distress, progressive pneumonia and in some cases respiratory failure and death.
Available controls:
AMPLIRUN® CORONAVIRUS SARS (2003) RNA CONTROL (Ref. MBC136-R)
El echovirus (Enteric Cytopathic Human Orphan virus) es un virus ARN que se transmite principalmente por vía fecal-oral. Existen más de 30 serotipos conocidos de echovirus que pueden causar de infecciones leves a enfermedades graves, como meningitis viral, encefalitis, miocarditis, hepatitis neonatal y exantemas virales.
Controles disponibles:
AMPLIRUN® ECHOVIRUS 5 RNA CONTROL (Ref. MBC064-R)
AMPLIRUN® ECHOVIRUS 11 RNA CONTROL (Ref. MBC149-R)
Parvovirus B19 is a small, non-enveloped, single-stranded DNA virus that belongs to the Parvoviridae family and exclusively infects humans. Parvovirus B19 infection is highly contagious and widespread among children. In most pediatric cases, it presents with mild symptoms including low-grade fever, headache, nasal congestion, and general malaise.
Acanthamoeba is a free-living amoeba that can cause severe keratitis in contact lens users and brain infections in immunocompromised individuals.
Available controls:
Neisseria meningitidis, or meningococcus, is a leading cause of bacterial meningitis. It spreads via respiratory droplets in close-contact environments and can lead to severe complications or death.
Available controls:
Enteroviruses, part of the Picornaviridae family, are small, non-enveloped positive-sense RNA viruses. They cause illnesses ranging from asymptomatic infections to aseptic meningitis, encephalitis, and poliomyelitis. Transmission is fecal-oral or respiratory, mainly affecting children.
Available controls:
Human parechoviruses (HPeV), from the Picornaviridae family, are small RNA viruses that can cause fever without source, clinical sepsis, meningitis, or encephalitis, mostly in infants.
Available controls:
Streptococcus agalactiae, also known as group B streptococcus (GBS), is part of the gastrointestinal and genital microbiota. In pregnant women, it can be transmitted to the newborn during delivery and cause sepsis, pneumonia or neonatal meningitis. It can also cause urinary tract or invasive infections in immunocompromised adults. Its detection is key in prenatal screening by culture or PCR.
Available controls:
AMPLIRUN® STREPTOCOCCUS AGALACTIAE DNA CONTROL (Ref. MBC071-R)
Cryptococcus neoformans is an encapsulated fungus found in plants and animals. It can cause cryptococcosis, an infection that mainly affects people with weakened immune systems. Its most serious form is cryptococcal meningitis, an infection of the brain that can affect the lungs and other organs.
Available controls:
AMPLIRUN® CRYPTOCOCCUS NEOFORMANS DNA CONTROL (Ref. MBC015-R)
Haemophilus influenzae is a gram-negative, coccobacillary, non-motile, facultative aerobic bacterium that can be part of the normal flora of the upper respiratory tract. It can cause bacterial meningitis, epiglottitis, pneumonia and septicemia among other diseases.
Available controls:
AMPLIRUN® HAEMOPHILUS INFLUENZAE DNA CONTROL (Ref. MBC020-R)
Listeria monocytogenes is a cold-resistant bacteria found in foods such as unpasteurized dairy products, sausages, smoked fish and poorly washed vegetables. It causes listeriosis infection, which can be especially serious in pregnant women, children and immunocompromised people.
Available controls:
AMPLIRUN® LISTERIA MONOCYTOGENES DNA CONTROL (Ref. MBC033-R)
Streptococcus pneumoniae is an encapsulated Gram-positive, immotile, facultative anaerobic coccus, usually occurring in pairs. It is an important respiratory pathogen that can cause otitis, sinusitis, pneumonia, meningitis and sepsis. It is identified by its sensitivity to optokine and solubility in bile. It particularly affects children, the elderly and immunocompromised individuals. Effective vaccines are available for its prevention.
Available controls:
AMPLIRUN® STREPTOCOCCUS PNEUMONIAE DNA CONTROL (Ref. MBC070-R)
Coxsackie is a group of enteroviruses belonging to the Picornaviridae family, which especially infect children and can cause a variety of viral illnesses, mostly self-limiting, although some can be severe.
Available controls:
AMPLIRUN® COXSACKIE B1 RNA CONTROL (Ref. MBC061-R)
AMPLIRUN® COXSACKIE B5 RNA CONTROL (Ref. MBC062-R)
AMPLIRUN® COXSACKIE A6 RNA CONTROL (Ref. MBC063-R)
Echovirus (Enteric Cytopathic Human Orphan virus) is an RNA virus that is mainly transmitted by the fecal-oral route. There are more than 30 known serotypes of echoviruses that can cause mild to severe infections such as viral meningitis, encephalitis, myocarditis, neonatal hepatitis and viral rashes.
Available controls:
AMPLIRUN® ECHOVIRUS 5 RNA CONTROL (Ref. MBC064-R)
AMPLIRUN® ECHOVIRUS 11 RNA CONTROL (Ref. MBC149-R)
Clostridium tetani is a Gram-positive, anaerobic, spore-forming bacterium responsible for tetanus. Its spores are highly resilient and can remain viable in soil for over 40 years. Infection occurs when the spores enter the body through open wounds or cuts, especially in low-oxygen environments, and germinate into active bacteria.
Epstein-Barr virus (EBV), part of the Herpesviridae family, causes infectious mononucleosis and is linked to some cancers. It is one of the most common viruses worldwide.
Available controls:
Herpes Simplex Virus (HSV), types 1 and 2, is widely prevalent. HSV-1 typically causes oral and ocular infections, while HSV-2 is associated with genital and neonatal infections.
Available controls:
Toxoplasma gondii is an intracellular protozoan that can cause severe disease in immunocompromised individuals and fetuses. Transmission occurs via contaminated meat, cat feces, or congenitally.
Available controls:
Cytomegalovirus (CMV) is a herpesvirus capable of latency after primary infection. It is a major cause of congenital infections and disease in immunocompromised individuals.
Available controls:
Rubella is an exanthematous viral disease, contagious but generally mild, whose main medical importance lies in its teratogenic effect when affecting pregnant women, which can cause congenital cataracts, deafness and congenital heart disease.
Available controls:
AMPLIRUN® RUBELLA RNA CONTROL (Ref. MBC113-R)
Brucellosis (Malta Fever) is a zoonotic disease caused by Brucella spp., transmitted to humans through unpasteurized dairy, direct animal contact, or infected aerosols. It can become chronic and persist for years.
Available controls:
Coxiella burnetii causes Q fever, a worldwide zoonosis that may present with fever, atypical pneumonia, hepatitis, or endocarditis. Serological diagnosis, especially phase I and II differentiation, is crucial to distinguish acute from chronic infections.
Available controls:
Borrelia spp. are motile spirochetes causing Lyme disease. B. burgdorferi sensu lato includes pathogenic species such as B. burgdorferi s.s., B. afzelii, and B. garinii, all found in Europe.
Available controls:
Francisella tularensis, the agent of tularemia, is a highly infectious bacterium transmitted through contact with wild animals, contaminated water, arthropod bites, or aerosol inhalation. Human-to-human transmission does not occur.
Available controls:
Echinococcus granulosus is a parasite that causes hydatid disease, leading to cyst formation in organs like the liver and lungs. Symptoms usually appear when cysts grow large and depend on their location
Monkeypox virus is a double-stranded DNA virus with an envelope, from the Orthopoxvirus genus. It is zoonotic, transmitted from rodents or primates to humans, with two main clades: West African and Central African.
Available controls:
AMPLIRUN® TOTAL MONKEYPOX VIRUS CONTROL (SWAB) (Ref. MBTC032-R)
AMPLIRUN® MONKEYPOX VIRUS DNA CONTROL (Ref.MBC146-R)
Ross River virus is an Alphavirus of the Togaviridae family endemic to Australia, Papua New Guinea and the Solomon Islands. It is transmitted by the bite of Aedes and Culex mosquitoes, with kangaroos and wallabies as the main reservoir. Although up to 30% of cases may be asymptomatic, the infection usually causes fever, arthralgias, rash and fatigue. Diagnosis is made by serology (IgM) or PCR.
Available controls:
AMPLIRUN® ROSS RIVER VIRUS RNA CONTROL (Ref. MBC130-R)
Bartonella is a genus of facultative intracellular gram-negative bacteria that includes species such as B. henselae, the agent of cat scratch disease. It is transmitted by vectors like fleas, lice, or scratches from infected animals, with cats being an important reservoir. Infection can be asymptomatic or cause fever, lymphadenopathy, endocarditis, or bacillary angiomatosis, especially in immunocompromised individuals. Diagnosis is based on serology, specialized culture, or PCR.
Available controls:
AMPLIRUN® BARTONELLA HENSELAE DNA CONTROL (Ref. MBC005-R)
AMPLIRUN® BARTONELLA QUINTANA DNA CONTROL (Ref. MBC006-R)
Leptospira biflexa is a non-pathogenic spirochete bacterium of the genus Leptospira, widely used as a model to study Leptospira biology and genetics due to its safety and ease of culture.
Available controls:
AMPLIRUN® LEPTOSPIRA BIFLEXA DNA CONTROL (Ref. MBC104-R)
Leptospira interrogans is the main pathogenic species of the genus. It causes leptospirosis, a zoonotic disease that can present with fever, jaundice, meningitis, renal and/or hepatic failure. It is transmitted by contact with infected animal urine, contaminated water or wet soil.
Acinetobacter baumannii is an opportunistic gram-negative bacterium associated with severe nosocomial infections, especially pneumonia, bacteraemia, urinary tract and wound infections. It is notable for its antimicrobial resistance and its ability to persist in hospital settings.
Enterobacter aerogenes is a gram-negative bacterium associated with opportunistic nosocomial infections. It can affect the urinary tract, respiratory tract, surgical wounds or the bloodstream.
Enterobacter cloacae is an opportunistic bacterium implicated in hospital-acquired infections, especially bacteraemia, pneumonia and urinary tract infections
Klebsiella pneumoniae is a gram-negative bacterium present in the gut microbiota, but potentially pathogenic. It can cause serious infections such as pneumonia, sepsis or urinary tract infections, and is associated with antimicrobial resistance.
Klebsiella oxytoca is a gram-negative bacterium associated with urinary and biliary tract infections. It shares similarities with K. pneumoniae, but differs in specific biochemical characteristics.
Proteus mirabilis is a gram-negative bacterium implicated in complicated urinary tract infections, especially in the presence of catheters. Its production of urease contributes to the formation of kidney stones.
Proteus vulgaris is an opportunistic gram-negative bacterium that can cause urinary tract, wound or liver infections, especially in immunocompromised patients.
Proteus penneri is a species related to P. mirabilis and P. vulgaris, mainly associated with nosocomial infections of the urinary tract, skin, soft tissues and blood.
Providencia rettgeri is a gram-negative bacterium found in the environment, associated with urinary tract infections and other opportunistic infections in hospital settings.
Providencia stuartii is an opportunistic pathogen that mainly affects patients with chronic urinary catheters, causing urinary tract infections and sepsis.
Staphylococcus saprophyticus is a gram-positive coccus that causes urinary tract infections, especially in young women. It has urease and the ability to adhere to the urogenital epithelium.
Citrobacter freundii is a Gram-negative bacterium of the Enterobacteriaceae family, present in the environment and in the human intestinal microbiota. It can cause nosocomial infections, especially in immunocompromised patients. Some strains show resistance to multiple antibiotics, such as carbapenemase-producing strains (blaKPC), making it an emerging pathogen in hospitals.
Citrobacter koseri is a Gram-negative bacterium that is part of the intestinal flora, but can cause opportunistic infections. It is known to be implicated in neonatal meningitis and brain abscesses, as well as urinary tract infections. It mainly affects immunocompromised patients and newborns.
Morganella morganii is an opportunistic pathogen that can cause infections mainly in hospitalized or immunocompromised patients. It can cause urinary tract infections, wound and abscess infections, sepsis or bacteremia among others.
Staphylococcus aureus is a common pathogen in nosocomial infections. It can cause anything from mild skin infections to severe disease such as pneumonia, sepsis or endocarditis.
Available controls:
AMPLIRUN® STAPHYLOCOCCUS AUREUS (mecA-) DNA CONTROL (Ref. MBC073-R)
AMPLIRUN® STAPHYLOCOCCUS AUREUS (mecA-) DNA CONTROL (Ref. MBC074-R)
Klebsiella pneumoniae is a gram-negative bacterium present in the gut microbiota, but potentially pathogenic. It can cause serious infections such as pneumonia, sepsis or urinary tract infections, and is associated with antimicrobial resistance.
Available controls:
AMPLIRUN® KLEBSIELLA PNEUMONIAE (NDM-1) DNA CONTROL (Ref. MBC107-R)
Enterococcus faecalis is a Gram-positive bacterium that is part of the human gut microbiota. Although normally commensal, it can cause serious opportunistic infections in hospital settings, such as endocarditis, urinary tract infections and bacteraemias. Its clinical importance lies in its ability to acquire resistance to multiple antibiotics, including vancomycin, which complicates its treatment.
Available controls:
AMPLIRUN® ENTEROCOCCUS FAECALIS (vanB) DNA CONTROL (Ref. MBC115-R)
Enterococcus faecium is a Gram-positive bacterium, usually commensal to the gut, but capable of causing serious infections in immunocompromised patients, such as neonatal meningitis or nosocomial infections. Like E. faecalis, it has developed resistance to several antibiotics, including vancomycin (VRE), which presents a challenge in hospitals.
Available controls:
AMPLIRUN® ENTEROCOCCUS FAECIUM (vanA) DNA CONTROL (Ref. MBC116-R)
Hepatitis delta virus (HDV) is a defective virus that requires hepatitis B virus (HBV) to replicate. It can worsen existing HBV infections and lead to chronic disease with symptoms resembling hepatitis B.
Hepatitis E virus (HEV) is mainly transmitted via the fecal-oral route or through contaminated food. It poses a particular risk to immunocompromised individuals and pregnant women, and is increasingly recognized in clinical settings.
Staphylococcus epidermidis is a skin commensal involved in nosocomial infections due to biofilm formation on medical devices. It is multidrug-resistant and causes sepsis, endocarditis and other infections.
Acanthamoeba castellanii is a free-living protozoan found in water, air and soil. It can cause human diseases such as amoebic keratitis, especially in contact lens wearers, and granulomatous amoebic encephalitis, a rare but fatal infection in immunocompromised patients. Its life cycle includes trophozoite and cystic forms, allowing it to survive in adverse conditions.
Available controls:
AMPLIRUN® ACANTHAMOEBA CASTELLANII DNA CONTROL (Ref. MBC054-R)
BK virus is a human polyomavirus that infects most people in childhood and remains latent in the body. It can reactivate in people with weakened immune systems causing serious complications, such as inflammation and damage of the kidney graft or hemorrhagic cystitis.
Available controls:
AMPLIRUN® BK VIRUS DNA CONTROL (Ref. MBC051-R)
Abiotrophia defectiva is a gram-positive bacterium that is part of the normal microbiota of the oral cavity, gastrointestinal and genitourinary tract, but can cause serious infections under special conditions, such as infective endocarditis.
Pseudomonas aeruginosa is an opportunistic gram-negative bacterium, widely distributed in the environment that can cause serious infections in immunocompromised individuals.
Serratia marcescens is an opportunistic gram-negative bacterium belonging to the Enterobacteriaceae family that can cause nosocomial infections especially in immunocompromised individuals or those with invasive medical devices.
JC virus is a human polyomavirus that infects most people at some point in their lives, usually during childhood. In healthy individuals, it usually remains latent, but can reactivate in immunocompromised individuals causing Progressive Multifocal Leukoencephalopathy (PML), a severe and potentially fatal brain disease.
Available controls:
AMPLIRUN® JC VIRUS DNA CONTROL (Ref. MBC150-R)